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Thermosensation

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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...

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Related Experiment Video

Updated: Jun 14, 2025

Membrane Potentials, Synaptic Responses, Neuronal Circuitry, Neuromodulation and Muscle Histology Using the Crayfish: Student Laboratory Exercises

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Neuromodulator-induced temperature robustness in a motor pattern: a comparative study between two decapod

Wolfgang Stein¹, Carola Städele²

¹School of Biological Sciences, Illinois State University, Normal, IL 61790, USA.

The Journal of Experimental Biology

|August 30, 2024

Summary

Neuropeptides enhance thermal tolerance in crab nervous systems by counteracting temperature-induced disruptions. This study shows neuropeptide modulation improves neuronal function across species, vital for poikilothermic animals.

Keywords:

Central pattern generator Crab Descending projection neuron Neuropeptide Stomatogastric ganglion

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Proprioception and Tension Receptors in Crab Limbs: Student Laboratory Exercises

Proprioception and Tension Receptors in Crab Limbs: Student Laboratory Exercises

Published on: October 24, 2013

Area of Science:

Neuroscience
Crustacean physiology
Environmental adaptation

Background:

Temperature fluctuations challenge nervous system function, especially in poikilothermic (cold-blooded) animals.
Neuronal systems must maintain function across a wide thermal range.
Previous work identified neuropeptide modulation as a thermal protection mechanism in Jonah crabs.

Purpose of the Study:

To investigate if neuropeptide modulation enhances temperature robustness in Dungeness and green crabs.
To determine if the mechanisms observed in Jonah crabs are conserved across related species.
To explore the cellular basis of neuropeptide-mediated thermal compensation.

Main Methods:

Electrophysiological recordings of the lateral gastric neuron in Dungeness and green crabs.
Analysis of the gastric mill pattern generator's rhythmic activity at varying temperatures.
Manipulation of neuronal activity and neuropeptide signaling.
Application of dynamic clamp to alter neuronal input resistance.

Main Results:

Elevated temperatures increased leak conductance and disrupted gastric mill rhythms in both crab species.
Increased descending modulatory input or neuropeptide application rescued rhythmic activity at higher temperatures.
Reducing input resistance via dynamic clamp partially restored rhythmicity, suggesting distinct compensation mechanisms.

Conclusions:

Neuropeptide modulation confers temperature robustness in Dungeness and green crabs, similar to Jonah crabs.
Neuropeptide-mediated thermal compensation is a conserved trait across these crab species.
The specific cellular mechanisms underlying this compensation may differ between species.