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Updated: Jun 14, 2025

In Vitro Polymerization of F-actin on Early Endosomes
Published on: August 28, 2017
Role of Rab GTPases in Bacteria Escaping from Vesicle Trafficking of Host Cells
Huiling Xu1, Shengnan Wang1,2, Xiaozhou Wang1
1College of Veterinary Medicine, Shandong Agricultural University, Tai`an, 271018, Shandong, People's Republic of China.
Abstract:
Most bacteria will use their toxins to interact with the host cell, causing damage to the cell and then escaping from it. When bacteria enter the cell, they will be transported via the endosomal pathway. Rab GTPases are involved in bacterial transport as major components of endosomes that bind to their downstream effector proteins. The bacteria manipulate some Rab GTPases, escape the cell, and get to survive. In this review, we will focus on summarizing the many processes of how bacteria manipulate Rab GTPases to control their escape.
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