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A Preclinical Model of Exertional Heat Stroke in Mice
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Rebound Hyperthermia in Exertional Heat Stroke
Preston J DeHan1, Shelley A Flores2, Blair B Rhodehouse3
1National Capital Consortium Primary Care Sports Medicine Fellowship, A.T. Augusta Military Medical Center, Fort Belvoir, VA 22060, USA.
Military Medicine
|August 30, 2024
Summary
Exertional heat stroke (EHS) requires rapid cooling. This case report shows endovascular cooling (EVC) successfully treated rebound hyperthermia after initial cooling failed, offering a new treatment approach for EHS.
Area of Science:
- Emergency Medicine
- Sports Medicine
- Physiology
Background:
- Exertional heat stroke (EHS) is a critical medical emergency characterized by hyperthermia.
- Prompt cooling is essential to prevent severe morbidity and mortality.
- Standard cooling methods may not always prevent temperature re-elevation.
Purpose of the Study:
- To report a case of exertional heat stroke with rebound hyperthermia.
- To highlight the successful use of endovascular cooling (EVC) in managing rebound hyperthermia in EHS.
- To suggest EVC as a potential treatment for refractory or rebound hyperthermia in EHS.
Main Methods:
- A case report of a 22-year-old male military recruit with EHS during a ruck march.
- Initial treatment involved conventional cooling methods (ice sheets, IV fluids).
- Endovascular cooling (EVC) was initiated due to rebound hyperthermia.
Main Results:
- The patient presented with a core temperature of 41.6°C.
- Initial cooling was effective, but rebound hyperthermia occurred upon cessation of conventional methods.
- Endovascular cooling successfully restored normothermia over 36 hours.
- No underlying pathology for rebound hyperthermia was identified, aside from foot cellulitis.
Conclusions:
- Endovascular cooling can be an effective treatment for rebound hyperthermia in exertional heat stroke.
- This case represents the first report of EVC successfully managing rebound hyperthermia in EHS.
- Further research into EHS-specific EVC protocols for refractory or rebound cases is warranted.
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