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Updated: Jun 14, 2025

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst
Published on: March 31, 2023
Vulvar epidermal cyst in a 54-year-old virgin female: A very rare case report
Mohammad Al-Jawad1, Mona Barakat1, Safinaz Dahoud1
1University of Aleppo, Faculty of Medicine, Aleppo, Syria.
Introduction:
Epidermal cysts are intradermal or subcutaneous tumors that can develop as a result of female genital mutilation (FGM) procedures or other traumatic events. The differential diagnosis of epidermal cysts in the vulvar or clitoral region depends on the age of presentation, with non-hormonal conditions like neurofibromatosis and nevus lipomatous cutaneous superficiality being considered in pediatric patients.
Case Presentation:
A 54-year-old female presented with urinary retention and a large vulvar mass. Imaging confirmed an epidermal cyst, which was surgically excised with successful resolution of the patient's symptoms and normal cosmetic appearance.
Discussion:
Epidermoid cysts are common benign lesions that can rarely occur on the vulva, including the labia minora. These cysts may be congenital or acquired and can cause discomfort or urinary obstruction when large. Thorough clinical evaluation and imaging are crucial for accurate diagnosis and surgical planning. Excision is often recommended, especially for large, symptomatic cysts, to manage the condition and obtain a definitive diagnosis.
Conclusion:
Vulvar epidermoid cysts, though rare, can occur on the labia minora. Differentiating these from other vulvar lesions and managing large, symptomatic cysts is challenging due to limited literature. This case highlights the need for comprehensive clinical evaluation, including history, exam, and imaging, to accurately diagnose and manage these rare cysts. Surgical excision is often recommended, considering potential complications. Further documentation is needed to improve the diagnosis and management of vulvar epidermoid cysts.
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