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Updated: Jun 14, 2025

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
Effectiveness of psychological interventions to decrease cognitive fusion in patients with chronic pain: A systematic
Susana Sanduvete-Chaves1, Salvador Chacón-Moscoso2, Francisco J Cano-García3
1Departamento de Psicología Experimental, Facultad de Psicología, Universidad de Sevilla, Seville, Spain.
Psychological interventions effectively reduce cognitive fusion in chronic pain patients. Further research is needed to fully understand its role in psychological flexibility.
Area of Science:
- Psychology
- Clinical Psychology
- Pain Management
Background:
- Acceptance and Commitment Therapy (ACT) is effective for chronic pain.
- Cognitive fusion, a core component of ACT, needs further investigation.
- The impact of psychological interventions on cognitive fusion in chronic pain is not well-established.
Purpose of the Study:
- To assess the effectiveness of psychological interventions in reducing cognitive fusion among chronic pain patients.
- To synthesize existing evidence on the impact of psychological therapies on cognitive fusion.
Main Methods:
- A systematic review of studies was conducted using major databases (Web of Science, SCOPUS, Medline, PsycINFO) up to June 2024.
- Studies included chronic pain patients undergoing psychological interventions with a cognitive fusion measure.
- Methodological quality was assessed, and effect sizes (Hedges g) were calculated.
Main Results:
- 18 articles comprising 24 studies were included (19 pre-post/follow-up, 5 RCTs).
- Cognitive fusion significantly decreased post-intervention (small/medium effect sizes: g = -0.39 at post-test, g = -0.55 at long-term follow-up).
- Similar significant reductions were observed in RCTs across follow-up periods, with medium effect sizes.
Conclusions:
- Psychological interventions demonstrate a tendency to decrease cognitive fusion in individuals with chronic pain.
- More clinical trials are required to definitively establish the role of cognitive fusion within the broader framework of psychological flexibility.
- Identified moderator variables include unemployment, gender, pain intensity, depression levels, and intervention characteristics.
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