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Related Concept Videos

Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

352
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
352
Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

545
Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
545
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

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The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
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Heart Failure Drugs: β-Blockers01:22

Heart Failure Drugs: β-Blockers

322
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
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Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

1.5K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.5K
Pulse rhythm01:30

Pulse rhythm

775
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
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Related Experiment Video

Updated: Jun 14, 2025

Author Spotlight: Workflow for Integrating POCUS Data into EHR for Managing Heart Failure Patients
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Author Spotlight: Workflow for Integrating POCUS Data into EHR for Managing Heart Failure Patients

Published on: July 12, 2024

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Digital tools in heart failure: addressing unmet needs.

Peder L Myhre1, Jasper Tromp2, Wouter Ouwerkerk3

  • 1Department of Cardiology, Akershus University Hospital, Lørenskog, Norway; KG Jebsen Center for Cardiac Biomarkers, University of Oslo, Oslo, Norway.

The Lancet. Digital Health
|August 30, 2024
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Summary

Digital tools offer new ways to manage heart failure, from screening to monitoring. Implementing these technologies globally is crucial for improving patient care, especially in underserved regions.

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Area of Science:

  • Cardiology
  • Digital Health
  • Health Informatics

Background:

  • Heart failure management faces challenges, particularly in low- and middle-income countries, despite effective therapies.
  • Rapid technological advancements and global connectivity create a favorable environment for digital health solutions.

Purpose of the Study:

  • To provide an overview of digital tools in heart failure care.
  • To explore the implications of these tools for heart failure research.
  • To emphasize the need for global implementation frameworks for digital health in cardiology.

Main Methods:

  • Literature review of digital tools in heart failure.
  • Analysis of current trends in technology and healthcare digitization.
  • Discussion of challenges and opportunities for digital health implementation.

Main Results:

  • Digital tools can enhance screening, diagnosis, treatment, and monitoring in heart failure.
  • These tools have significant potential to improve patient outcomes and advance research.
  • Global adoption is hindered by the need for robust clinical frameworks and supportive ecosystems.

Conclusions:

  • Digital health tools are pivotal for advancing heart failure care and research.
  • Establishing global frameworks is essential for equitable access and effective utilization.
  • Further development and integration of digital solutions are critical for overcoming existing management inadequacies.