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Related Concept Videos

Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
Clipper Circuit01:18

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A clipper circuit is a fundamental wave-shaping device that harnesses the unique properties of diodes to alter and control waveform characteristics. This technology is widely used in electronic devices, especially in television and radar communication systems, where it enhances waveform modulation in both transmitters and receivers.
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Clamper Circuit01:14

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A clamper circuit, also known as a DC restorer, represents a specialized variant of the rectifier circuit, notable for its method of taking the output across the diode rather than the capacitor. This configuration lends to several distinctive applications, particularly in handling square wave inputs.
Within this circuit, the diode's orientation prompts the capacitor to charge up to the level of the most negative peak of the input signal. Upon reaching this state, the diode ceases to conduct,...

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How i do it: individualized bypass strategy with tentative clamping method.

Long Wang1, Lujun Jing2, Ao Pei3

  • 1Department of Neurosurgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, PR China. wanglong@mail.ccmu.edu.cn.

Acta Neurochirurgica
|August 31, 2024
PubMed
Summary

Cerebral revascularization (CR) is key for symptomatic hemisphere with misery perfusion (SHMP). Tentative clamping method (TCM) minimizes risks and improves cognition in this neurosurgical procedure.

Keywords:
Cerebral ischemicCerebral revascularizationHemispheric hypo-perfusionMiddle cerebral artery occlusionSuperficial temporal artery

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Area of Science:

  • Neurosurgery
  • Vascular Neurology

Background:

  • Cerebral revascularization (CR) is crucial for managing symptomatic hemisphere with misery perfusion (SHMP).
  • Progressive middle cerebral artery steno-occlusion presents a significant clinical challenge.

Purpose of the Study:

  • To describe the application of a tentative clamping method (TCM) for cerebral revascularization.
  • To demonstrate the efficacy of TCM in managing progressive middle cerebral artery steno-occlusion.

Main Methods:

  • A case study of a middle-aged gentleman with progressive middle cerebral artery steno-occlusion.
  • Individualized arterial reconstruction using the tentative clamping method (TCM).
  • Intraoperative monitoring and an accompanying operative video were utilized.

Main Results:

  • The tentative clamping method (TCM) was successfully employed for cerebral revascularization.
  • The procedure aimed to minimize postoperative adverse events.
  • Improved neuro-cognitive status was observed post-procedure.

Conclusions:

  • Optimal treatment for SHMP requires an individualized approach.
  • The tentative clamping method (TCM) is a viable prophylactic procedure for CR.
  • TCM can minimize risks and enhance neuro-cognitive outcomes in patients with SHMP.