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Updated: Jun 14, 2025
Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
Published on: November 17, 2023
Highly sensitive SERS detection of melamine based on 3D Ag@porous silicon photonic crystal
Wei Li1, Shijie Dai2, Xiang Li3
1School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, 210023, China; Medical Imaging Center, the First Affiliated Hospital, Jinan University, Guangdong, 510630, China.
Abstract:
The stability, reproducibility and engineering of SERS substrate faces a great challenge in melamine SERS assay. In this work, a simple, highly sensitive, stable and cost-efficient SERS detection platform for melamine was established based on its Raman fingerprints spectrum. The Ag@ porous silicon photonic crystal (Ag@PPC) was prepared as the 3D SERS substrate by electrochemical etching and magnetron sputter technology. The main influence factors for the preparation of SERS substrate were investigated in detail. The analytical enhancement factor of the 3D SERS substrate can reach to 2.6 × 108. The 3D SERS detection platform showed a wide linear detection range of 10-4∼10 mg L-1 and a low limit of detection of 0.1 μg L-1 for melamine. Moreover, such detection platform showed good stability, high reproducibility and high recovery rates for melamine. The 3D Ag@PPC SERS substrate can be easily prepared and engineered, displaying a great potential application in food safety field.
