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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
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Cancer mortality trends in Luxembourg: A 24-year descriptive study (1998-2021).

Allini Mafra1, Jérôme Weiss2, Stéphanie Saleh2

  • 1Cancer Epidemiology and Prevention Group (EPI CAN), Public Health Expertise Unit, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.

Cancer Epidemiology
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Cancer mortality rates in Luxembourg significantly decreased from 1998-2021, with notable declines in lung and breast cancer deaths. However, late adulthood women saw increases in laryngeal and lung cancer mortality.

Keywords:
CancerEuropeLuxembourgMortalityTrends

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Area of Science:

  • Epidemiology
  • Public Health
  • Oncology

Background:

  • Cancer is a leading global cause of death, necessitating robust epidemiological studies for effective control strategies.
  • Understanding cancer burden and trends is crucial for public health planning and intervention development.

Purpose of the Study:

  • To analyze temporal changes in cancer mortality rates in Luxembourg between 1998 and 2021.
  • To examine these trends by sex and age group for specific cancer types.

Main Methods:

  • Utilized data from Luxembourg's National Registry of Death Causes (1998-2021) and population statistics.
  • Calculated age-standardized mortality rates (ASRs) per 100,000, adjusted to the European standard population.
  • Employed the Average Annual Percentage Changes (AAPC) method to assess significant temporal trends.

Main Results:

  • Identified 23,750 cancer deaths, with an overall ASR of 152.86 per 100,000 annually.
  • Lung cancer was the leading cause of cancer death in men and combined sexes; breast cancer in women.
  • Observed significant overall decreases in ASR for both sexes, including prostate and breast cancers, though increases in laryngeal and lung cancer mortality were noted in older women.

Conclusions:

  • The study offers a comprehensive analysis of cancer mortality trends in Luxembourg, informing public health policy and cancer control planning.
  • Highlights the need for targeted interventions like early detection, screening programs, and continued treatment advancements.