Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

427
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
427

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mincle-dependent Th17 adjuvanticity requires TNFR1 signaling in myeloid cells.

Frontiers in immunology·2026
Same author

<i>Coxiella burnetii</i> infects osteoclasts and alters their differentiation and function in a type IV secretion system-dependent manner.

Frontiers in immunology·2026
Same author

Histo-Miner: Deep learning based tissue features extraction pipeline from H&E whole slide images of cutaneous squamous cell carcinoma.

PLoS computational biology·2026
Same author

Allergy diagnostic performance of FastCheckPOC 20 Atopy.

Frontiers in allergy·2025
Same author

Peptide Epitopes of NC16A BP180 in the Diagnostics of Bullous Pemphigoid.

JID innovations : skin science from molecules to population health·2025
Same author

Association of allergen stability and epithelial barrier function in sensitized patients.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2025

Related Experiment Video

Updated: May 5, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

21.4K

Prediction of Clinically Significant Prostate Cancer Using Multiparametric MRI, Biparametric MRI, and Clinical

Maximilian Oberneder1, Thomas Henzler2, Martin Kriegmair1

  • 1Urologische Klinik München-Planegg, Planegg, Germany.

Urologia Internationalis
|September 1, 2024
PubMed
Summary

Contrast-enhanced MRI (mpMRI) offers minimal benefit for prostate cancer detection. Non-contrast MRI (bpMRI) is a viable alternative, demonstrating comparable diagnostic performance to mpMRI for clinically significant prostate cancer (csPCa).

Keywords:
Biparametric MRIDynamic contrast enhanced MRIMultiparametric MRIProstate cancerProstate-specific antigen density

More Related Videos

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking
05:49

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Published on: October 10, 2019

6.5K
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

146

Related Experiment Videos

Last Updated: May 5, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

21.4K
Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking
05:49

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Published on: October 10, 2019

6.5K
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

146

Area of Science:

  • Radiology
  • Oncology
  • Medical Imaging

Background:

  • Multiparametric MRI (mpMRI) is the standard for diagnosing clinically significant prostate cancer (csPCa).
  • Assessing the value of perfusion sequences and the non-inferiority of non-contrast MRI (bpMRI) compared to mpMRI is crucial.

Purpose of the Study:

  • To evaluate the added benefit of dynamic contrast-enhanced (DCE) sequences in mpMRI for csPCa detection.
  • To determine if bpMRI is non-inferior to mpMRI in diagnosing csPCa, considering clinical parameters.

Main Methods:

  • Retrospective analysis of MRI data from 355 biopsy-naïve patients.
  • Data acquired using a 3T MRI system and evaluated by an experienced radiologist.
  • Subsequent mpMRI-TRUS fusion biopsy was performed for diagnosis.

Main Results:

  • Only 4.5% of patients benefited from DCE sequences.
  • bpMRI missed only 0.8% of csPCa cases, showing comparable sensitivity (81.4%) and specificity (79.4%) to mpMRI (75.2%; 81.8%).
  • Both bpMRI and mpMRI were independent predictors of csPCa, with PSA density showing the highest diagnostic performance (AUC=0.81).

Conclusions:

  • The study confirms that bpMRI is a non-inferior alternative to mpMRI for csPCa diagnosis.
  • bpMRI should be considered for clinical adoption, pending further validation in multi-reader studies.
  • Clinical parameters, particularly PSA density, significantly aid in csPCa detection.