Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Receiver Operating Characteristic Plot01:15

Receiver Operating Characteristic Plot

104
A ROC (Receiver Operating Characteristic) plot is a graphical tool used to assess the performance of a binary classification model by illustrating the trade-off between sensitivity (true positive rate) and specificity (false positive rate). By plotting sensitivity against 1 - specificity across various threshold settings, the ROC curve shows how well the model distinguishes between classes, with a curve closer to the top-left corner indicating a more accurate model. The area under the ROC curve...
104
Detection of Gross Error: The Q Test01:00

Detection of Gross Error: The Q Test

5.7K
When one or more data points appear far from the rest of the data, there is a need to determine whether they are outliers and whether they should be eliminated from the data set to ensure an accurate representation of the measured value. In many cases, outliers arise from gross errors (or human errors) and do not accurately reflect the underlying phenomenon. In some cases, however, these apparent outliers reflect true phenomenological differences. In these cases, we can use statistical methods...
5.7K
Cut-off Frequency of BJT01:17

Cut-off Frequency of BJT

657
Cut-off frequencies in Bipolar Junction Transistors (BJTs) mark the transition between the signal's pass band and stop band, influencing their performance in amplifying or attenuating frequencies. These frequencies are crucial for designing BJTs to meet specific operational requirements in electronic circuits.
Alpha Cut-Off Frequency: Pertinent to the common-base configuration, the alpha cut-off frequency defines the upper-frequency limit at which the current gain, alpha, remains stable. As...
657
Decision Making: P-value Method01:09

Decision Making: P-value Method

5.3K
The process of hypothesis testing based on the P-value method includes calculating the P- value using the sample data and interpreting it.
First, a specific claim about the population parameter is proposed. The claim is based on the research question and is stated in a simple form. Further, an opposing statement to the claim  is also stated. These statements can act as null and alternative hypotheses:  a null hypothesis would be a neutral statement while the alternative hypothesis can...
5.3K
Finding Critical Values for Chi-Square01:18

Finding Critical Values for Chi-Square

2.9K
Consider a curve representing sample data drawn randomly from a normally distributed population. One must construct confidence intervals to estimate or to test a claim regarding the population standard deviation. For example, a 95% confidence interval covers 95% of the area under the curve, and the remaining 5% is equally distributed on either side of the curve. To achieve such confidence intervals, one must determine the critical values. The critical values are simply the values separating the...
2.9K
Quantifying and Rejecting Outliers: The Grubbs Test01:02

Quantifying and Rejecting Outliers: The Grubbs Test

1.5K
Sometimes, a data set can have a recorded numerical observation that greatly  deviates from the rest of the data. Assuming that the data is normally distributed, a statistical method called the Grubbs test can be used to determine whether the observation is truly an outlier.  To perform a two-tailed Grubbs test, first, calculate the absolute difference between the outlier and the mean. Then, calculate the ratio between this difference and the standard deviation of the sample. This...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Likelihood ratios of quantitative diagnostic test results.

Scandinavian journal of clinical and laboratory investigation·2026
Same author

Interpreting two test results of one analyte from the same individual using bivariate reference values.

Scandinavian journal of clinical and laboratory investigation·2026
Same author

Divide or subtract: transferrin saturation versus unbound iron binding capacity (UIBC).

Scandinavian journal of clinical and laboratory investigation·2026
Same author

Sample stability of forty-two analytes in plasma or serum pools after one to four repeated -80 °C freeze-thaw cycles.

Scandinavian journal of clinical and laboratory investigation·2025
Same author

Combining the calibrator uncertainty and the long-term measurement uncertainty? A comment to the ISO/TS 20914 guideline.

Clinical chemistry and laboratory medicine·2025
Same author

Testing MMA<sub>100</sub> - the eGFR-adjusted concentration of methylmalonic acid in plasma.

Scandinavian journal of clinical and laboratory investigation·2025

Related Experiment Video

Updated: Jun 14, 2025

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.4K

The optimal cut-off value

Arne Åsberg1, Bjørn Johan Bolann2

  • 1Department of Clinical Chemistry, St. Olav's Hospital, POB 3250 Torgarden, 7006 Trondheim, Norway.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|September 1, 2024
PubMed
Summary

No abstract available in PubMed .

Keywords:
BenefitCostDecision analysisLikelihood ratioROC curve analysis

More Related Videos

Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
09:16

Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method

Published on: May 12, 2023

1.1K
Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
14:06

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

Published on: June 23, 2012

15.2K

Related Experiment Videos

Last Updated: Jun 14, 2025

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.4K
Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
09:16

Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method

Published on: May 12, 2023

1.1K
Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
14:06

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

Published on: June 23, 2012

15.2K