Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Standardized Reporting of Cardiac Magnetic Resonance Examinations in Children With Cardiac Diseases and Adults With Congenital Heart Disease: A Scientific Statement From the Association for European Pediatric and Congenital Cardiology (AEPC) and the International Society for Magnetic Resonance in Medicine (ISMRM).

Journal of magnetic resonance imaging : JMRI·2026

Same author

A Comparison of Tissue Property Values Estimated Using Conventional Cardiac MRF and MT-Cardiac MRF.

Magnetic resonance in medicine·2026

Same author

Imaging Near Spinal Fixation Hardware at 0.55 T Compared With 3 T.

Journal of magnetic resonance imaging : JMRI·2026

Same author

OpenMRF: A Modular, Vendor-Neutral Open-Source Framework for Reproducible Magnetic Resonance Fingerprinting using Pulseq.

ArXiv·2026

Same author

Magnetic resonance fingerprinting of the bladder is feasible in men with lower urinary tract symptoms.

Abdominal radiology (New York)·2026

Same author

Improved dynamic MRI of the wrist and heart at 0.55 T enabled by rapid 3D printed flexible coils.

Nature communications·2026

Search research articles

Related Experiment Video

Updated: Jun 14, 2025

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

T1 and T2 measurements across multiple 0.55T MRI systems using open-source vendor-neutral sequences.

Kathryn E Keenan¹, Bilal Tasdelen², Ahsan Javed³

¹National Institute of Standards and Technology, Boulder, Colorado, USA.

Magnetic Resonance in Medicine

|September 2, 2024

Summary

This summary is machine-generated.

Quantitative T1 and T2 measurements at 0.55T MRI are consistent between prototype and commercial systems. This finding applies to both phantom and healthy participant data, ensuring reliable imaging across different hardware.

Keywords:

0.55T T1 T2 multi‐site repeatability

More Related Videos

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Related Experiment Videos

Last Updated: Jun 14, 2025

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Area of Science:

Magnetic Resonance Imaging (MRI)
Biomedical Engineering
Medical Physics

Background:

Standardization of quantitative MRI measurements is crucial for reliable clinical applications.
Assessing the comparability of prototype and commercial MRI systems ensures hardware interoperability and consistent diagnostic accuracy.
0.55T MRI systems offer a balance between cost and image quality, making them relevant for various clinical settings.

Purpose of the Study:

To compare T1 and T2 relaxation time measurements between prototype and commercial 0.55T MRI systems.
To evaluate the consistency of quantitative MRI metrics using vendor-neutral pulse sequences and analysis methods.
To assess the performance of 0.55T MRI systems in both phantom and healthy participant studies.

Main Methods:

Utilized standard spin echo and abbreviated protocols for T1, B1, and T2 measurements on four 0.55T MRI systems (two prototype, two commercial).
Employed an ISMRM/NIST system phantom for phantom studies and imaged five healthy participants across all systems.
Compared phantom measurements to NMR-based references for accuracy and assessed reproducibility and system differences using both phantom and in vivo data.

Main Results:

Successfully implemented vendor-neutral pulse sequences and reconstruction methods, with code made freely available.
Demonstrated no statistically significant differences in mean T1 and T2 relaxation times between prototype and commercial systems in healthy participants.
Observed no significant differences in phantom T1 and T2 measurements between the prototype and commercial systems using the abbreviated protocol.

Conclusions:

Quantitative T1 and T2 measurements at 0.55T are statistically comparable across prototype and commercial MRI systems.
The findings support the interchangeability of prototype and commercial 0.55T MRI hardware for quantitative imaging.
Vendor-neutral approaches ensure consistent quantitative MRI results regardless of system manufacturer.