Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanism of Ciliary Motion01:05

Mechanism of Ciliary Motion

3.6K
The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
The cilia are made up of microtubules in a 9+2 arrangement, with nine microtubule doublet ring bundles, surrounding a pair of central singlet microtubule bundles. The doublet microtubule bundles are...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The hippocampus as a small-world cognitive map.

bioRxiv : the preprint server for biology·2026
Same author

Helical opto-thermoviscous flows drive out-of-plane rotation and particle spinning in a highly viscous micro-environment.

Light, science & applications·2026
Same author

One-stop strabismus digital diagnosis via AI-integrated skin-like and wearable "Eyelectronics".

Science advances·2026
Same author

Rotation reversal of chiral bacterial vortices.

Soft matter·2025
Same author

How tp1, an indirect wing steering muscle, stabilizes <i>Drosophila's</i> flight.

bioRxiv : the preprint server for biology·2025
Same author

Modal analysis and optimization of swimming active filaments.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2025
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026
Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026
Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026
Same journal

Vision-guided parallel manipulation of cells with optoelectronic tweezers.

Lab on a chip·2026
Same journal

Review of nanofluidic mass transport systems: engineering through physicochemical fields and interfacial properties.

Lab on a chip·2026
See all related articles

Related Experiment Video

Updated: Jun 14, 2025

Cardiac Muscle Cell-based Actuator and Self-stabilizing Biorobot - Part 2
09:33

Cardiac Muscle Cell-based Actuator and Self-stabilizing Biorobot - Part 2

Published on: May 9, 2017

8.7K

Electronically actuated artificial hinged cilia for efficient bidirectional pumping.

Wei Wang1,2,3, Ivan Tanasijevic4,5, Jinsong Zhang1

  • 1Laboratory of Atomic and Solid State Physics, Cornell University, Ithaca, New York, 14850, USA. ww459@cornell.edu.

Lab on a Chip
|September 2, 2024
PubMed
Summary
This summary is machine-generated.

Engineered hinged cilia achieve bidirectional fluid pumping, overcoming limitations of previous micro-cilial platforms. This innovation enables greater fluid volumes and broader frequency ranges for microscale fluid manipulation.

More Related Videos

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

13.8K
Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1
11:22

Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1

Published on: July 11, 2017

8.1K

Related Experiment Videos

Last Updated: Jun 14, 2025

Cardiac Muscle Cell-based Actuator and Self-stabilizing Biorobot - Part 2
09:33

Cardiac Muscle Cell-based Actuator and Self-stabilizing Biorobot - Part 2

Published on: May 9, 2017

8.7K
High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

13.8K
Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1
11:22

Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1

Published on: July 11, 2017

8.1K

Area of Science:

  • Microfluidics and Nanotechnology
  • Biomimetics and Bio-inspired Engineering

Background:

  • Cilia-based pumping is crucial for microscale fluid control, with electronically driven platforms offering arbitrary flow patterns.
  • Previous micro-cilial platforms faced limitations, including unidirectional pumping, complex bidirectional flow generation, and restricted operating frequencies due to elastic and viscous coupling.

Purpose of the Study:

  • To design and demonstrate a novel micro-cilial platform inspired by natural cilia's complex internal structure.
  • To overcome the limitations of previous platforms by enabling bidirectional pumping and operation over a broader frequency range.

Main Methods:

  • Development of hinged cilia, mimicking the complex internal structure of natural cilia.
  • Experimental actuation and characterization of hinged cilia arrays for fluid manipulation.
  • Demonstration of arbitrary flow pattern generation using individually controlled hinged cilia arrays.

Main Results:

  • Hinged cilia achieve bidirectional pumping, significantly increasing fluid volumes per cycle compared to previous designs.
  • The new design allows operation over a broad range of frequencies, overcoming previous operational restrictions.
  • Arrays of controlled hinged cilia can generate diverse flow patterns with higher efficiency and fewer cilia.

Conclusions:

  • Hinged cilia represent a significant advancement in microfluidic pumping, inspired by natural systems.
  • This technology offers enhanced control over microscale fluid transport, with potential for broader engineering applications.
  • The ability to generate complex flow patterns with fewer elements reduces fabrication complexity and increases efficiency.