Related Experiment Video
Updated: Jun 14, 2025

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
Published on: April 4, 2022
Relapsing polychondritis after COVID-19 vaccination.
Koki Ito1, Takunori Ogawa1, Shunya Igarashi1
1Division of Infectious Diseases and Respiratory Medicine, Department of Internal Medicine National Defense Medical College Saitama Japan.
Relapsing polychondritis (RP) is a rare autoimmune disease. This report details the first strong association found between COVID-19 vaccination and the development of RP, highlighting a potential risk after mRNA vaccines.
Area of Science:
- Immunology
- Rheumatology
- Vaccinology
Background:
- Relapsing polychondritis (RP) is a rare systemic autoimmune disorder.
- It is characterized by the immune-mediated destruction of cartilaginous tissues.
- The etiology of RP remains largely unknown, with potential triggers under investigation.
Related Concept Videos
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:

