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Updated: Jun 14, 2025

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
Calcinosis Cutis Inducing "Syringomatoid" Eccrine Hyperplasia: An Extremely Rare Example
Umar A Hussain1, Audrey E Ahuero2, Jamie A Tschen3
1Histopathology, Manchester University NHS Foundation Trust, Manchester, GBR.
Abstract:
Reactive "syringomatoid" eccrine proliferations are a well-established phenomenon, which can show similar but less extensive histological features of a syringoma. The cut-off between syringomatoid hyperplasia and syringomas is subjective and given the considerable morphological overlap, it is possible they represent two points on the same spectrum. Syringomatoid hyperplasia has been associated with several conditions including neoplasms and inflammatory dermatoses. Herein, we describe an extremely rare case of syringomatoid hyperplasia occurring with calcinosis cutis in a 54-year-old Caucasian male. To the best of the authors' knowledge, this is the first such case described in the literature.
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