Hive-shaped carbon nanotubes coated with MoSe₂as an electrochemical sensor for cholesterol

The study utilized transition metal chalcogenide, molybdenum diselenide (MoSe₂), for application in the field of bioelectrochemical sensing. The MoSe₂was combined with carbon nanotubes (CNTs) by chemical vapor deposition to enhance the specific surface area and improve the detection sensitivity. To further increase the contact area between the electrolyte and the electrode, photolithography techniques were employed to fabricate hive-shaped CNTs, thereby enhancing the specific surface area. Next, cholesterol oxidase (ChOx) was coated onto the electrode material, creating a cholesterol biosensor. Cyclic voltammetry was utilized to detect the concentration of cholesterol. The experiment involved segmented testing for cholesterol concentrations ranging from 0μM to 10 mM. Excellent sensitivity, low detection limits, and high accuracy were achieved. In the cholesterol concentration range of 0μM-100μM, the experiment achieved the highest sensitivity of 4.44μAμM⋅cm^-2. Consequently, all data indicated that ChOx/MoSe₂/CNTs functioned as an excellent cholesterol sensor in the study.