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Updated: Sep 22, 2026

Prostaglandin Extraction and Analysis in Caenorhabditis elegans
Published on: June 25, 2013
Eicosanoids as bioregulators in clinical medicine
Abstract:
Formation of eicosanoids in stimulated cells and tissues is a ubiquitous phenomenon, but the precise physiologic or pathophysiologic role of these autacoids has not yet been defined. In contrast, understanding of synthetic mechanisms, metabolism, and catabolism of eicosanoids seems to have surpassed understanding of their pharmacologic actions. Early clinical research involving eicosanoids focused on reactions of the cyclo-oxygenase pathway, which are inhibitable by nonsteroidal anti-inflammatory drugs. The lipoxygenase pathway, which appears to be an important component of the allergic and inflammatory response, represents a new area of clinical research.
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