Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Percutaneous umbilical blood sampling.

J C Hobbins, P A Grannum, R Romero

    American Journal of Obstetrics and Gynecology
    |May 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Fetoscopic repair of spina bifida: safer and better?

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2016
    Same author

    Identification of novel cell survival regulation in diabetic embryopathy via phospholipidomic profiling.

    Biochemical and biophysical research communications·2016
    Same author

    Decreased fetal cardiac performance in the first trimester correlates with hyperglycemia in pregestational maternal diabetes.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2011
    Same author

    At diabetes-like concentration, glucose down-regulates the placental serotonin transport system in a cell-cycle-dependent manner.

    Journal of neurochemistry·2007
    Same author

    A consensus report of the Diabetes in Pregnancy Study Group of North America Conference, Little Rock, Arkansas, May 2002.

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2003
    Same author

    Blood glucose monitoring in gestational diabetes mellitus: 1- versus 2-h blood glucose determinations.

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2003
    Same journal

    Likelihood ratios enhance clinical interpretation of metagenomic prediction of early-onset neonatal sepsis in preterm premature rupture of membranes (Letter-to-the-Editor).

    American journal of obstetrics and gynecology·2026
    Same journal

    Taking risk stratification in preterm premature rupture of membranes to the bedside (Reply to Letter-to-the-Editor).

    American journal of obstetrics and gynecology·2026
    Same journal

    Gestational Age at Full-Term Delivery and Long-Term Offspring Morbidity in Low-Risk Pregnancies: A Population-Based Cohort Study.

    American journal of obstetrics and gynecology·2026
    Same journal

    Trajectories of childbirth-related posttraumatic stress symptoms after a vaginal delivery: a multicenter prospective study.

    American journal of obstetrics and gynecology·2026
    Same journal

    Early life adversity and polycystic ovary syndrome among North American pregnancy planners.

    American journal of obstetrics and gynecology·2026
    Same journal

    Survival assessment of adjuvant chemotherapy for cytology-negative, non-myoinvasive stage IC clear cell endometrial cancer.

    American journal of obstetrics and gynecology·2026
    See all related articles

    Sonographically guided percutaneous umbilical blood sampling offers rapid fetal circulation access for diagnosing and managing second and third-trimester pregnancy complications. This technique aids in assessing risks like hemostatic failure, chromosomal disorders, and fetal hypoxia.

    Area of Science:

    • Perinatology
    • Fetal Medicine
    • Diagnostic Ultrasound

    Background:

    • Prenatal diagnosis is crucial for managing high-risk pregnancies.
    • Second and third-trimester diagnostic challenges require fetal assessment.
    • Accessing fetal circulation enables comprehensive prenatal evaluation.

    Observation:

    • A technique for sonographically guided percutaneous umbilical blood sampling was developed.
    • The procedure provides direct access to fetal circulation.
    • This method was applied to 13 fetuses requiring prenatal assessment.

    Findings:

    • The technique successfully obtained fetal blood samples.
    • It facilitated the diagnosis of hemostatic failure (hemophilia, idiopathic thrombocytopenic purpura).

    Related Experiment Videos

  • Chromosomal disorders, isoimmunization, and fetal hypoxia were also assessed.

    • Implications:

    • Sonographically guided percutaneous umbilical blood sampling is a valuable tool for prenatal diagnosis.
    • The procedure supports timely management of various fetal conditions.
    • It offers both diagnostic and potential therapeutic applications in high-risk pregnancies.