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Updated: Jun 14, 2025

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
[Research progress on the extracorporeal membrane oxygenation intubation-related infection]
1Department of Cardiopulmonary Bypass, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100037, China. Corresponding author: Gao Guodong,
Abstract:
Extracorporeal membrane oxygenation (ECMO) is commonly a transitional treatment way used in patients with severe heart and lung problem. Deoxidized blood is extracted through venous intubation, and then returned to the arterial or venous system after oxygenation. There is a risk of intubation-related infection in arterial or venous intubation. Once the infection occurs, it will prolong the patient's length of hospitalization stay, increase the mortality and medical expenses. Longer duration of ECMO and higher simplified acute physiology score (SAPS) were risk factors for infection. At present, the main diagnostic method for infection is blood culture. Ultrasound-guided percutaneous cannulation can reduce the occurrence of infection; if infection still occurs, antibiotics should be actively treated. In order to bring reference for clinical work, this article reviews the incidence, risk factors, diagnostic criteria, prevention strategies, treatment methods and other key points of ECMO intubation-related infection.
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