Technologies for investigating single-molecule chemical reactions

Area of Science:

• Chemistry
• Physics
• Materials Science
• Biology

Background:

• Single molecules are the fundamental building blocks of matter.
• Studying single-molecule chemical reactions provides molecular-scale insights into reaction mechanisms.
• This understanding is crucial for addressing scientific challenges in diverse fields.

Purpose of the Study:

• To provide a comprehensive overview of single-molecule chemical reactions.
• To highlight various technical platforms used for studying these reactions.
• To discuss current research perspectives and future opportunities.

Main Methods:

• Scanning probe microscopy
• Single-molecule junction techniques
• Single-molecule nanostructure analysis
• Single-molecule fluorescence detection
• Crossed molecular beam experiments

Main Results:

• Multidimensional analyses of single-molecule chemical reactions offer new research perspectives.
• Applications span photocatalysis, electrocatalysis, organic reactions, surface reactions, and biological reactions.
• The review consolidates knowledge on diverse technical platforms.

Conclusions:

• Single-molecule chemical reactions are a vital and thriving research area.
• Further research is needed to overcome existing challenges and unlock new opportunities.
• This field holds significant potential for advancing fundamental science and technological applications.