Relationship between gut microbiota and multiple sclerosis: a scientometric visual analysis from 2010 to 2023

Area of Science:

• Microbiology
• Neuroimmunology
• Bibliometrics

Background:

• Gut microbiota (GM) plays a significant role in multiple sclerosis (MS).
• A systematic scientometric analysis is lacking to understand the research landscape of GM in MS.
• This study addresses this gap by analyzing publications from 2010-2023.

Purpose of the Study:

• To conduct a scientometric analysis of research on the link between gut microbiota and multiple sclerosis.
• To identify key research trends, institutions, authors, and future directions in this field.
• To provide a comprehensive overview of the current research status for scientists.

Main Methods:

• A quantitative and visual scientometric analysis was performed.
• Data was collected from 2010 to 2023.
• CiteSpace and VOSviewer software were utilized for analysis.

Main Results:

• A total of 1019 records were analyzed, showing a consistent annual increase in publications.
• The United States led in publications and international collaboration.
• Key research areas include GM alterations in MS/EAE, immunological mechanisms, and interventions, with keywords like inflammation, probiotics, diet, and dysbiosis being prominent.
• Emerging research focuses on neurodegeneration and neuropsychiatric disorders.

Conclusions:

• This study provides a systematic, data-driven understanding of GM research in MS over 13 years.
• It highlights significant research contributions and identifies current trends and future research hotspots.
• The findings serve as a valuable reference for researchers entering the field of gut microbiota and multiple sclerosis.