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Related Experiment Video

Updated: Jun 14, 2025

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

Myocardial calcification: case reports and a systematic review.

Takashi Kido¹, Kazuki Tanimoto¹, Takuji Watanabe¹

¹Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2, Yamada-Oka, Suita, Osaka 565-0871, Japan.

European Heart Journal. Imaging Methods and Practice

|September 3, 2024

Summary

Myocardial calcification, an unusual calcium buildup in the heart muscle, is often linked to sepsis and myocarditis. Computed tomography (CT) findings may improve with treatment of the underlying condition.

Keywords:

myocardial calcification myocarditis sepsis

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Last Updated: Jun 14, 2025

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

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Published on: June 2, 2022

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

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Published on: August 28, 2018

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

Area of Science:

Cardiology
Radiology
Pathology

Background:

Myocardial calcification is characterized by excess calcium deposition in the heart muscle.
This condition is uncommon and can be associated with various underlying pathologies.

Purpose of the Study:

To report two cases of myocardial calcification.
To conduct a systematic review of the clinical course and associated pathologies of myocardial calcification.

Main Methods:

Systematic review of PubMed and Scopus databases.
Inclusion criteria: case reports/series, CT diagnosis, adequate patient data, English publication.
Analysis of 75 patients with myocardial calcification.

Main Results:

Commonly associated conditions included sepsis (24 patients) and myocarditis (14 patients).
Mortality rates varied: 33% with sepsis, 14% with myocarditis, 11% with other pathologies.
CT findings of calcification persisted but showed regression over time; autopsy revealed fibrosis and inflammation.

Conclusions:

Sepsis and myocarditis are frequently reported comorbidities of myocardial calcification.
Computed tomography (CT) findings of myocardial calcification may regress with successful treatment of the underlying disease.