Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

5.8K
Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
5.8K
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

3.3K
Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
3.3K
Proteomics01:33

Proteomics

7.5K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.5K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

836
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
836
Microbial Biosensors01:17

Microbial Biosensors

88
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
88
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

77
Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
77

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent advances in functional studies of coronavirus NSP13 helicase and challenges in inhibitor development.

Virulence·2026
Same author

Dynamic nutritional trajectories and deterioration risk in esophageal cancer radiotherapy: a prospective study.

Frontiers in nutrition·2026
Same author

Enhancing Phosphorus Availability Through Bagasse Biochar Addition and Changes in <i>phoD</i> Bacterial Communities of Karst and Non-Karst Forest Soils.

Microorganisms·2026
Same author

The emerging roles of alternative splicing in modulating tumor immune responses and immunotherapies.

Cell death and differentiation·2026
Same author

Targeting non-canonical antigens unlocks functional T-cell responses in renal cell carcinoma.

Journal for immunotherapy of cancer·2026
Same author

Matrigel/serum-free, high-fidelity patient-derived tumor-like cell clusters as an in vitro platform for large-scale compound screening and chemoresistance prediction in oral cancer.

BMC medicine·2026

Related Experiment Video

Updated: May 3, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.4K

Advances in microneedle technology for biomedical detection.

Xinmei Zhang1, Yuemin Wang1, Xinyu He1

  • 1College of Medicine, Southwest Jiaotong University, Chengdu 610003, China. chenxingyu55555@126.com.

Biomaterials Science
|September 3, 2024
PubMed
Summary
This summary is machine-generated.

Microneedle technology offers a painless, minimally invasive method for real-time biomedical detection. This approach integrates various sensing techniques for applications like glucose monitoring and wound infection assessment.

More Related Videos

Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.1K
Fabrication of Fine Electrodes on the Tip of Hypodermic Needle Using Photoresist Spray Coating and Flexible Photomask for Biomedical Applications
08:15

Fabrication of Fine Electrodes on the Tip of Hypodermic Needle Using Photoresist Spray Coating and Flexible Photomask for Biomedical Applications

Published on: November 28, 2017

9.6K

Related Experiment Videos

Last Updated: May 3, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.4K
Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.1K
Fabrication of Fine Electrodes on the Tip of Hypodermic Needle Using Photoresist Spray Coating and Flexible Photomask for Biomedical Applications
08:15

Fabrication of Fine Electrodes on the Tip of Hypodermic Needle Using Photoresist Spray Coating and Flexible Photomask for Biomedical Applications

Published on: November 28, 2017

9.6K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Nanotechnology

Background:

  • Microneedles are small devices capable of penetrating the skin's surface.
  • They offer a platform for localized and real-time detection.
  • Integration with various detection methods enhances their utility.

Purpose of the Study:

  • To review the integration of detection methods with microneedle technology.
  • To explore microneedle applications in biomedical detection.
  • To assess the future potential and challenges of this technology.

Main Methods:

  • Summarization of common detection methods (colorimetric, electrochemical, spectrometric, fluorescence) combined with microneedles.
  • Showcasing exemplary uses in biomedical contexts.
  • Review of literature on microneedle-based detection.

Main Results:

  • Microneedles can be combined with various detection techniques for biomedical sensing.
  • Applications include blood glucose monitoring, wound infection assessment, point-of-care testing, and biomarker identification.
  • Microneedle-based detection is painless, minimally invasive, and biocompatible.

Conclusions:

  • Microneedle detection technology holds significant promise for enhancing biological assays.
  • It has transformative potential for personalized medicine and healthcare.
  • Future development requires addressing associated challenges.