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Endoscopic Combined Intrarenal Surgery: best practices and future perspectives.
Anderson B Pellanda1, Fabio C M Torricelli1, John Denstedt2
1Divisão de Urologia, Departamento de Cirurgia, Faculdade de Medicina da Universidade de São Paulo - USP, São Paulo, SP, Brasil.
Summary
Endoscopic Combined Intrarenal Surgery (ECIRS) offers superior stone-free rates and fewer complications for large kidney stones compared to Percutaneous Nephrolithotomy (PCNL). Further research is recommended to establish ECIRS as a primary treatment option.
Area of Science:
- Urology
- Minimally Invasive Surgery
Background:
- Endoscopic Combined Intrarenal Surgery (ECIRS) is a developing technique for managing large and complex kidney stones.
- It may offer advantages over traditional Percutaneous Nephrolithotomy (PCNL).
Purpose of the Study:
- To evaluate best practices, outcomes, and future perspectives of ECIRS.
- To compare ECIRS with PCNL for kidney stone management.
Main Methods:
- A comprehensive literature search was performed on PubMed from 2008 to 2024.
- Included studies compared ECIRS and PCNL, analyzing indications, access, outcomes, and complications.
Main Results:
- ECIRS showed higher stone-free rates and lower complication rates than PCNL.
- ECIRS may reduce the need for repeat procedures and can integrate new technologies.
Conclusions:
- ECIRS presents significant advantages for treating large kidney stones.
- Well-designed randomized controlled trials are needed to confirm efficacy, safety, and cost-effectiveness.
- ECIRS could become the preferred treatment for complex kidney stones.

