Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Organization of the Nervous System01:13

Organization of the Nervous System

5.7K
The nervous system is one of the most complex systems in our body. It is organized into two main divisions: the central nervous system (CNS) and the peripheral nervous system (PNS).
The CNS, comprising the brain and spinal cord, houses billions of neurons. The brain is housed in the skull, while the spinal cord is linked to the brain through the foramen magnum of the occipital bone and is surrounded by the protective structure of the vertebral column. It is responsible for processing various...
5.7K
Neural Circuits01:25

Neural Circuits

1.1K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.1K
Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

1.7K
The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

USP29 and SMURF1 orchestrate FSP1-mediated ferroptosis suppression to facilitate chemoresistance in gastric cancer.

Nature communications·2025
Same author

Deep convolutional and fully-connected DNA neural networks.

Nature communications·2025
Same author

Olverembatinib, a multikinase inhibitor that modulates lipid metabolism, in advanced succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 1b study and translational research.

Signal transduction and targeted therapy·2025
Same author

Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8.

Cell death & disease·2024
Same author

The circMYBL2-Encoded p185 Protein Suppresses Colorectal Cancer Progression by Inhibiting Serine Biosynthesis.

Cancer research·2024
Same author

Local Excision Versus Radical Resection for Grade 2 Rectal Neuroendocrine Tumors: A Multicenter Propensity Score-Matched Analysis.

Diseases of the colon and rectum·2024
Same journal

Inhibiting PPM1D Perturbs Mitochondrial Integrity to Stimulate cGAS-STING Signaling and Antitumor Immunity.

Cancer research·2026
Same journal

BRD9 Degraders Unleash GBAF Chromatin Remodeling Activity in Synovial Sarcoma.

Cancer research·2026
Same journal

Virtual Tumors Enable Prediction of Personalized Therapeutic Combinations for Non-Small Cell Lung Cancer.

Cancer research·2026
Same journal

Opportunities to enhance cancer research through advocate-researcher partnerships.

Cancer research·2026
Same journal

EGFR N-Glycosylation Catalyzed by NDST2 Promotes Lenvatinib Resistance in Hepatocellular Carcinoma.

Cancer research·2026
Same journal

Immune checkpoint blockade augments lymphodepleting chemotherapy-induced antitumor immunity by expanding effector CD8+ T cell clones.

Cancer research·2026
See all related articles

Related Experiment Video

Updated: Jun 14, 2025

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
05:39

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

347

Neural Circuitries between the Brain and Peripheral Solid Tumors.

Xiang Chen1, Yuli Geng2, Guanxin Wei1

  • 1Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Cancer Research
|September 3, 2024
PubMed
Summary
This summary is machine-generated.

The brain and tumors communicate bidirectionally, influencing each other

More Related Videos

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
08:59

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma

Published on: January 5, 2017

10.6K
In Vitro Modeling of Cancerous Neural Invasion: The Dorsal Root Ganglion Model
08:23

In Vitro Modeling of Cancerous Neural Invasion: The Dorsal Root Ganglion Model

Published on: April 12, 2016

9.1K

Related Experiment Videos

Last Updated: Jun 14, 2025

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
05:39

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

347
A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
08:59

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma

Published on: January 5, 2017

10.6K
In Vitro Modeling of Cancerous Neural Invasion: The Dorsal Root Ganglion Model
08:23

In Vitro Modeling of Cancerous Neural Invasion: The Dorsal Root Ganglion Model

Published on: April 12, 2016

9.1K

Area of Science:

  • Neuroscience
  • Oncology
  • Cancer Biology

Background:

  • The central nervous system (CNS) plays a critical role in tumor initiation and progression.
  • Bidirectional communication exists between the brain and tumors.
  • Tumors can influence brain activity, and the brain can affect tumor cell behavior.

Purpose of the Study:

  • To review the latest research on brain-tumor cross-talk.
  • To explore neural circuitries between the brain and peripheral solid tumors.
  • To analyze molecular mediators and pathologic mechanisms involved in tumor development.

Main Methods:

  • Literature review of recent studies on brain-tumor interactions.
  • Analysis of neural pathways and molecular signaling.
  • Synthesis of current understanding of cancer biology.

Main Results:

  • The brain influences tumor biology via neural, endocrine, and immune systems.
  • Tumors establish neural networks to signal the CNS, affecting brain activity.
  • Understanding these interactions is crucial for cancer biology.

Conclusions:

  • Reciprocal brain-tumor communication is a significant area of research.
  • This understanding provides a basis for novel cancer treatment strategies.
  • Repurposing psychiatric interventions for cancer treatment is a potential avenue.