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Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxy-PEP-Eligible Population
Rachel Mittelstaedt1,2, Sanjat Kanjilal3,4, David Helekal2
1Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Medrxiv : the Preprint Server for Health Sciences
|September 4, 2024
Abstract:
In Staphylococcus aureus infections in men eligible for doxycycline post-exposure prophylaxis (doxy-PEP), tetracycline non-susceptibility is more prevalent than in the overall population and is associated with resistance to trimethoprim-sulfamethoxazole and clindamycin. Doxy-PEP may select for S. aureus multi-drug resistance, underscoring the importance of surveillance.
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