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Updated: Jun 14, 2025

Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry
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Streamlining LC-MS Characterization of Pharmaceutical Polymers by Fourier-Transform-Based Deconvolution and

Andrew K Swansiger1, Christopher M Crittenden2, Simon A Chan2

  • 1Department of Chemistry and Biochemistry, 1253 University of Oregon, Eugene, Oregon 97403-1253, United States.

Analytical Chemistry
|September 4, 2024
PubMed
Summary

Polymer conjugation improves biotherapeutics, but analysis is complex. This study introduces a new method using Fourier transform-based deconvolution for streamlined pharmaceutical polymer characterization and reaction monitoring.

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