Brain tumor detection and segmentation using deep learning

Brain tumor detection, classification and segmentation are challenging due to the heterogeneous nature of brain tumors. Different deep learning-based algorithms are available for object detection; however, the performance of detection algorithms on brain tumor data has not been widely explored. Therefore, we aim to compare different object detection algorithms (Faster R-CNN, YOLO & SSD) for brain tumor detection on MRI data. Furthermore, the best-performing detection network is paired with a 2D U-Net for pixel-wise segmentation of abnormal tumor cells.

The proposed model was evaluated on the Brain Tumor Figshare (BTF) dataset, and the best-performing detection network cascaded with 2D U-Net for pixel-wise segmentation of tumors. The best-performing detection network was also fine-tuned on BRATS 2018 data to detect and classify the glioma tumor.

For the detection of three tumor types, YOLOv5 achieved the highest mAP of 89.5% on test data compared to other networks. For segmentation, YOLOv5 combined with 2D U-Net achieved a higher DSC compared to the 2D U-Net alone (DSC: YOLOv5 + 2D U-Net = 88.1%; 2D U-Net = 80.5%). The proposed method was compared with the existing detection and segmentation network i.e. Mask R-CNN and achieved a higher mAP (YOLOv5 + 2D U-Net = 89.5%; Mask R-CNN = 67%) and DSC (YOLOv5 + 2D U-Net = 88.1%; Mask R-CNN = 44.2%).

In this work, we propose a deep-learning-based method for multi-class tumor detection, classification and segmentation that combines YOLOv5 with 2D U-Net. The results show that the proposed method not only detects different types of brain tumors accurately but also delineates the tumor region precisely within the detected bounding box.