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Processing imbalanced medical data at the data level with assisted-reproduction data as an example.

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Summary
This summary is machine-generated.

Data imbalance in medical data mining impacts model reliability. This study found optimal cut-offs of 15% positive rate and 1500 samples for logistic models, recommending SMOTE and ADASYN for imbalanced datasets.

Keywords:
Imbalanced dataImbalanced data processing methodImbalanced degreeLogistic modelSample size

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Area of Science:

  • Medical data mining
  • Machine learning in healthcare
  • Predictive modeling

Background:

  • Data imbalance is a significant challenge in medical data mining, leading to biased predictive models.
  • Effective strategies are needed to mitigate the impact of imbalanced data on classification model performance.

Purpose of the Study:

  • Quantify effects of data imbalance and sample size on model performance.
  • Identify optimal cut-off values for positive rates and sample sizes.
  • Evaluate methods for enhancing model accuracy in imbalanced and small sample size scenarios.

Main Methods:

  • Collected medical records from assisted reproductive treatment.
  • Used random forest for variable screening.
  • Constructed datasets with varying imbalance degrees and sample sizes to compare logistic regression models.
  • Applied SMOTE, ADASYN, OSS, and CNN for imbalance treatment.

Main Results:

  • Logistic model performance improved beyond 10% positive rate and 1200 samples.
  • Optimal cut-offs identified as 15% positive rate and 1500 samples for model stability.
  • SMOTE and ADASYN significantly enhanced classification performance in imbalanced, small datasets.

Conclusions:

  • A positive rate of 15% and sample size of 1500 are optimal for stable logistic model performance.
  • SMOTE and ADASYN are recommended for improving balance and accuracy in low positive rate and small sample size datasets.