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Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

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Published on: December 15, 2017

Advancing sustainable biotechnology through protein engineering.

Amelia R Bergeson¹, Hal S Alper²

¹McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA.

Trends in Biochemical Sciences

|September 5, 2024

Summary

Engineered enzymes offer a greener alternative to traditional industrial chemistry. This review explores their use in sustainability applications like carbon capture, biofuels, and waste degradation.

Keywords:

bioremediation enzyme engineering fuel processing green manufacturing greenhouse gas sequestration plastic recycling

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Area of Science:

Biotechnology and Industrial Chemistry
Enzyme Engineering
Sustainable Industrial Processes

Background:

Traditional industrial chemistry often involves harsh conditions and hazardous reagents.
There is a growing need for sustainable alternatives in industrial processes.
Enzymes offer a biologically-based and often environmentally benign approach.

Purpose of the Study:

To highlight the role of engineered enzymes in advancing industrial sustainability.
To identify key application areas where enzyme engineering is crucial.
To suggest future directions for enzyme engineering efforts.

Main Methods:

Review of current literature on engineered enzymes in industrial applications.
Analysis of enzyme properties such as activity, stability, and novel functions.
Identification of successful enzyme applications in specific sectors.

Main Results:

Engineered enzymes demonstrate significant potential as replacements for traditional chemical catalysts.
Key applications include greenhouse gas sequestration, fuel production, bioremediation, and plastic waste degradation.
Enzyme engineering has successfully enhanced performance for these demanding industrial tasks.

Conclusions:

Engineered enzymes are pivotal for achieving industrial sustainability goals.
Further advancements in enzyme engineering will unlock new applications and improve existing ones.
The shift towards biocatalysis represents a greener future for the chemical industry.