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Updated: May 10, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
The emerging role of Artificial Intelligence in proton therapy: A review
Lars Johannes Isaksson1, Federico Mastroleo1, Maria Giulia Vincini2
1Division of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan 20141, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan 20141, Italy.
Abstract:
Artificial intelligence (AI) has made a tremendous impact in the space of healthcare, and proton therapy is not an exception. Proton therapy has witnessed growing popularity in oncology over recent decades, and researchers are increasingly looking to develop AI and machine learning tools to aid in various steps of the treatment planning and delivery processes. This review delves into the emergent role of AI in proton therapy, evaluating its development, advantages, intended clinical contexts, and areas of application. Through the analysis of 76 studies, we aim to underscore the importance of AI applications in advancing proton therapy and to highlight their prospective influence on clinical practices.
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