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Related Concept Videos

Factors Influencing Drug Absorption: Pharmaceutical Parameters01:28

Factors Influencing Drug Absorption: Pharmaceutical Parameters

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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
123

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Generation of Alginate Microspheres for Biomedical Applications
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Alginate Capsules: Versatile Applications and Production Techniques.

Francesca Passannanti1,2, Marianna Gallo1,2,3, Giulia Lentini1

  • 1Department of Chemical Engineering, Materials, and Industrial Production, University of Naples Federico II, P. Tecchio 80, Naples, 80125, Italy.

Macromolecular Bioscience
|September 5, 2024
PubMed
Summary
This summary is machine-generated.

Alginate capsules, derived from brown algae, offer versatile applications across industries due to their unique crosslinking properties. This review explores their production methods and diverse uses, highlighting their potential in various fields.

Keywords:
alginatedrug deliveryencapsulationnutraceuticalsshelflife

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Food Science

Background:

  • Alginate, a natural polysaccharide from brown algae, functions as a food additive (thickener, gelling, emulsifier).
  • Its polyanionic structure enables crosslinking with divalent/trivalent cations, forming solid matrices.
  • This crosslinking allows for the encapsulation of various compounds into capsules or beads.

Purpose of the Study:

  • To review the primary techniques for producing alginate capsules.
  • To showcase diverse application fields for alginate encapsulation technology.

Main Methods:

  • Crosslinking of alginate chains via ionic interactions with cations.
  • Formation of capsules or beads for compound encapsulation.

Main Results:

  • Alginate capsules can protect, deliver, or control the release of encapsulated ingredients.
  • Potential applications span pharmaceuticals, nutrition, agri-food, textiles, and cosmetics.
  • Alginate capsules can function as micro-reactors.

Conclusions:

  • Alginate encapsulation is a versatile technology with broad industrial applicability.
  • The review details production methods and highlights numerous potential uses.
  • Alginate's properties make it a valuable biomaterial for advanced applications.