Case Report: A Case Report on an 18-Year-Old Female with Cerebral Vasculitis in Systemic Lupus Erythematosus (SLE)

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Updated: Jul 20, 2026

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
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A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

Published on: July 28, 2018

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Sakshi Dudhe1, Gaurav V Mishra1, Pratap Singh Parihar1

  • 1Department of Radio-Diagnosis,, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.

F1000Research
|September 5, 2024
PubMed

Insights

Systemic Lupus Erythematosus (SLE) can cause severe cerebral vasculitis, leading to neurological decline. This case highlights the critical need for early diagnosis and improved treatments for SLE-related central nervous system vasculitis.

Area of Science:

  • Neurology
  • Rheumatology
  • Immunology

Background:

  • Systemic Lupus Erythematosus (SLE) is an autoimmune disease with potential neurological complications.
  • Cerebral vasculitis is a rare but serious manifestation of SLE, posing diagnostic and therapeutic challenges.

Observation:

  • An 18-year-old female with known SLE presented with seizures, cognitive decline, and unresponsiveness.
  • Diagnostic workup, including neurological examination, labs, and imaging, confirmed cerebral vasculitis secondary to SLE.

Findings:

  • Despite aggressive immunosuppressive therapy, the patient experienced neurological deterioration.
  • The patient developed respiratory failure and multiorgan dysfunction, ultimately succumbing to complications of CNS vasculitis.

Implications:

  • This case emphasizes the critical need for prompt recognition and aggressive management of SLE-related cerebral vasculitis.
  • Further research is essential to develop more effective therapies for central nervous system vasculitis in SLE patients to improve outcomes.

Keywords:
cerebral vasculitisimmunological dysfunctionmultiorgan failureneurological complicationssystemic lupus erythematosus (SLE)treatment challenges

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