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Surgical Management of Complicated Thoracic Fungal Infections: A Case Series from a Tertiary Referral Center
Josephine Guitton1, Jonathan Livezey2, Andrew Anklowitz2
1Medical College of Georgia, Augusta, Georgia, USA.
Abstract:
Although rare in the general population, pulmonary fungal infections usually occur in immunocompromised patients. The mainstay of pulmonary fungal infection treatment is prolonged intravenous antifungal therapy. However, surgical management may be required in cases of complex disease, resistance to medical therapy or percutaneous procedures, or associated complications such as fungal empyema and massive hemoptysis. In this series, we present three patients with complicated thoracic fungal infections who underwent individualized surgical management over a 3-month period in 2022 at our institution. Complicated pulmonary fungal infections require surgical intervention to ensure complete resolution. The choice of operation is dependent on several factors, and surgeons operating on these patients must be privy to the various surgical modalities that may be required to successfully treat these patients.
Insights
Surgical intervention is crucial for complicated pulmonary fungal infections, especially in immunocompromised patients. Individualized surgical approaches ensure complete resolution when medical therapy fails.
Area of Science:
- Pulmonology
- Infectious Diseases
- Thoracic Surgery
Background:
- Pulmonary fungal infections are rare but serious, primarily affecting immunocompromised individuals.
- Standard treatment involves prolonged intravenous antifungal therapy.
- Surgical intervention becomes necessary for complex cases, treatment resistance, or complications like fungal empyema and hemoptysis.
Purpose of the Study:
- To present a series of patients with complicated thoracic fungal infections.
- To highlight the role of individualized surgical management in resolving these complex infections.
Main Methods:
- Retrospective review of three patients with complicated thoracic fungal infections.
- Detailed description of individualized surgical interventions performed over a 3-month period in 2022.
Main Results:
- Successful resolution of complicated fungal infections in all three patients through tailored surgical procedures.
- Demonstration of the feasibility and effectiveness of surgical management in challenging cases.
Conclusions:
- Complicated pulmonary fungal infections often necessitate surgical intervention for complete resolution.
- Surgeons must be knowledgeable about various surgical modalities to effectively treat these patients.
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