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Updated: Jun 14, 2025

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Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products
Published on: August 22, 2017
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Ciprofloxacin's Structure Causing Fluoride-Related Toxicity: A Case Report
Nadielle Silva Bidu1,2,3, Silvana Trinchão Costa1,3, Ricardo David Couto1,3,4
1Pharmacy Postgraduate Program, Faculty of Pharmacy, Federal University of Bahia/UFBA, Salvador, Bahia, Brazil.
Current Drug Safety
|September 5, 2024
Summary
This study reports a case of ciprofloxacin-induced fluoride toxicity. High urinary fluoride levels were linked to tendinopathy and peripheral neuropathy, highlighting a potential risk of this common antibiotic.
Area of Science:
- Pharmacology
- Toxicology
- Neurology
Background:
- Ciprofloxacin, a fluoroquinolone antibiotic, contains fluorine.
- Known side effects include tendinopathy, neuropathy, and cardiotoxicity.
- The toxicological effect of ciprofloxacin fluoride at elevated urinary levels is undocumented.

