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Clinical Features, Imaging Use, And Management In Giant Cell Arteritis: A Retrospective Single-center Study.

Home
Research Domains
History, Heritage And Archaeology
Historical Studies
European History (excl. British, Classical Greek And Roman)
Clinical Features, Imaging Use, And Management In Giant Cell Arteritis: A Retrospective Single-center Study.

Related Experiment Video

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Clinical features, imaging use, and management in giant cell arteritis: a retrospective single-center study.

Aradhna Agarwal¹, Reid Weisberg², Jiby Mathew³

¹Internal Medicine, UT Southwestern Medical Center, Dallas, USA. aradhna.agarwal92@gmail.com.

Clinical Rheumatology

|September 5, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Giant cell arteritis (GCA) diagnosis is challenging due to varied symptoms. Rheumatologists improve GCA management with advanced imaging and specific treatments, suggesting multidisciplinary clinics enhance patient care.

Keywords:

Arteritis Diagnostic imaging Giant cell arteritis Systemic vasculitis

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Area of Science:

Rheumatology
Internal Medicine
Vascular Medicine

Background:

Giant cell arteritis (GCA) is a vasculitis with diverse presentations, complicating diagnosis.
Current diagnostic pathways and management strategies show variability across medical specialties.

Purpose of the Study:

To characterize patients diagnosed with GCA.
To evaluate imaging utilization in GCA diagnosis.
To analyze differences in GCA management among specialties.

Main Methods:

Retrospective analysis of Dallas VAMC database (2010-2021) using ICD codes and temporal artery biopsy (TAB) records.
Inclusion criteria required meeting ACR 1990 classification criteria for GCA.
Statistical analysis included Fisher's exact test for categorical and Kruskal-Wallis for continuous variables.

Main Results:

The cohort (n=168) was 91.9% male, median age 69; 42 received a GCA diagnosis, 15 with positive TAB.
Presenting symptoms included visual disturbances (75.5%) and headaches (67.7%); ophthalmology was the initial specialty for 46%.
Rheumatologists were more likely to use advanced imaging and prescribe glucocorticoid-sparing treatments (p<0.05).

Conclusions:

GCA diagnosis is challenging due to heterogeneous symptoms; headache and scalp tenderness were more frequent in GCA patients.
Vascular assessments and advanced imaging are underutilized in GCA diagnosis.
Multidisciplinary or fast-track clinics may optimize GCA diagnosis and management.