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Ureteral pseudodiverticulosis.

N F Wasserman, S La Pointe, I P Posalaky

    Radiology
    |June 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Small ureteral pseudodiverticula are uncommon. While urine cytology missed early cancers, cellular atypia in patients with ureteral pseudodiverticulosis warrants close follow-up due to potential malignancy.

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    Area of Science:

    • Urology
    • Pathology

    Background:

    • Ureteral diverticula, particularly small ones (<4 mm), are rarely reported and often appear as pseudodiverticula in pathological specimens.
    • Previous studies suggest a potential association between ureteral diverticula and transitional cell carcinoma (TCC) of the urinary tract.

    Purpose of the Study:

    • To report on a series of patients with ureteral pseudodiverticula, focusing on clinical presentation and diagnostic findings.
    • To evaluate the utility of urine cytologic studies in detecting malignancy in patients with ureteral pseudodiverticulosis.

    Main Methods:

    • Retrospective review of 23 patients with ureteral pseudodiverticula.
    • Diagnostic workup included urinalysis, urine culture, cystoscopy, and urine cytologic studies in 15 patients.

    Main Results:

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    • The majority of diverticula were multiple (91%), bilateral (69%), and located in the upper/mid-ureter.
    • Common presenting conditions included hematuria, transitional cell carcinoma, and benign prostatic hyperplasia.
    • Urine cytology failed to detect early uroepithelial malignancy but showed nonspecific cellular atypia in some patients.

    Conclusions:

    • Ureteral pseudodiverticulosis is frequently associated with malignancy (30% in this series).
    • Close patient follow-up is recommended due to the observed association with malignancy and cellular atypia.