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Related Concept Videos

Cholinergic Antagonists: Therapeutic Uses01:26

Cholinergic Antagonists: Therapeutic Uses

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Antimuscarinic drugs have various therapeutic applications by inhibiting parasympathetic stimulation in different systems. Here are the key therapeutic uses of antimuscarinics:    
Respiratory Tract: Ipratropium, aclidinium, and tiotropium treat asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). They protect against bronchoconstriction caused by irritants like cigarette smoke, sulfur dioxide, and ozone. They also help reduce nasopharyngeal...
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Antiasthma Drugs: Muscarinic Receptor Antagonists01:20

Antiasthma Drugs: Muscarinic Receptor Antagonists

261
Muscarinic receptor antagonists, also known as antimuscarinic agents, are a class of bronchodilators used to treat asthma, although they are more commonly used to treat COPD. They work by inhibiting the action of acetylcholine (ACh), a neurotransmitter, on muscarinic receptors found in the airways.
Antimuscarinic agents compete with ACh for the same binding site on the muscarinic receptors. By binding to these receptors, they inhibit the downstream effects of ACh and block the parasympathetic...
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Direct-Acting Cholinergic Agonists: Therapeutic Uses01:11

Direct-Acting Cholinergic Agonists: Therapeutic Uses

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Direct-acting cholinergic agonists have many therapeutic uses in various medical fields. Choline esters, including acetylcholine, have limited clinical utility due to their non-selectivity and short duration of action. Still, acetylcholine and carbachol are applied topically during ophthalmologic surgery to induce miosis. Pilocarpine, a muscarinic and ganglionic stimulator, effectively treats open-angle glaucoma and alleviates xerostomia and dry mouth caused by radiotherapy or Sjögren...
704

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Related Experiment Video

Updated: Jun 14, 2025

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
04:59

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Severe itch from miliaria managed with propantheline: a case report.

Ronald Wai1,2, Brodie Sheahen3,4, Benjamin Thomas5,6

  • 1Palliative Medicine, Illawarra Shoalhaven Local Health District, Wollongong, New South Wales, Australia ronald.k.h.wai@gmail.com.

BMJ Supportive & Palliative Care
|September 5, 2024
PubMed
Summary

A persistent, distressing itch in a palliative care patient with cancer was successfully treated. The case highlights diagnosis and management of miliaria, a common cause of pruritis in this setting.

Area of Science:

  • Palliative Care Medicine
  • Dermatology

Background:

  • Itch (pruritis) is a prevalent and distressing symptom in palliative care.
  • Older adults with advanced cancer are susceptible to various conditions causing pruritis.
Keywords:
Palliative CarePruritisQuality of lifeSupportive care

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