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Updated: Jun 14, 2025

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
Published on: March 24, 2015
Unweaving type I interferons in age-related neuroinflammation
David P J Hunt1, Markus J Hofer2
1UK Dementia Research Institute at University of Edinburgh, Edinburgh, EH16 4SB, UK; Centre for Clinical Brain Sciences at University of Edinburgh, Edinburgh, EH16 4SB, UK.
None:
Neuroinflammation is a feature of both neurodegenerative disease and normal brain aging. The roles of type I interferon (IFN-I) in the aged brain are incompletely understood. A recent article by Roy et al. reveals pervasive IFN-I activity in normal mouse brain aging, and highlights the importance of microglial IFN-I signaling in neuroinflammation.
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