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CD133 in T-lymphoblastic leukemia is preferentially expressed in early T-phenotype (ETP) and near ETP subtypes

Shuyu E1, Karen Amelia Nahmod1, Beenu Thakral1

  • 1Department of Hematopathology, UT MD Anderson Cancer Center, Houston, Texas, USA.

Cytometry. Part B, Clinical Cytometry
|September 5, 2024
PubMed
Abstract

No abstract available in PubMed .

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T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...

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