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Intracholecystic Papillary Neoplasm: A Case Report
Sham Taqwa1, Daiki Soma2, Kathleen Ehresmann2
1Surgery, University of Jordan, Amman, JOR.
Cureus
|September 6, 2024
Summary
A rare gallbladder neoplasm, intracholecystic papillary neoplasm (ICPN) with high-grade dysplasia, was incidentally discovered in a 30-year-old female. This finding highlights the importance of pathological examination for potential malignant transformation.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Gallstones and gallbladder polyps are common findings.
- Robotic cholecystectomy is a minimally invasive surgical approach.
- Intracholecystic papillary neoplasm (ICPN) is a rare gallbladder lesion.
Observation:
- A 30-year-old female presented with symptomatic gallstones and polyps.
- Pathological examination of the gallbladder revealed an incidental ICPN with high-grade dysplasia.
- The patient underwent robotic cholecystectomy.
Findings:
- The case highlights an incidental diagnosis of ICPN with high-grade dysplasia.
- High-grade dysplasia in ICPN indicates a significant risk of malignant transformation.
- This underscores the importance of thorough pathological evaluation post-cholecystectomy.
Implications:
- Early detection of ICPN is crucial for preventing gallbladder cancer.
- This case contributes to the literature on rare gallbladder neoplasms.
- Routine pathological examination of gallbladders is essential for identifying potentially malignant lesions.

