[Spectrophotometric method of determining phenoxymethylpenicillin in the air]

A modified spectrophotometric method is recommended for the control of the air condition at pharmaceutical plants manufacturing phenoxymethylpenicillin and its dosage forms. The method is based on measuring absorption of the mixture solutions at two (258 and 268) and three (253, 268 and 261) wave lengths. The limit of the measuring in the solution volume is 0.015 mg. The air samples are collected on filters AFA-VP-20 or AFA-KHP-20 at an aspiration rate of 15-20 l/min and then the antibiotic is extracted in a 0.04 per cent solution of sodium bicarbonate.