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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Jun 14, 2025

Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction
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Radially Emitting Diode Laser Closure of Transsphincteric Fistula-in-Ano.

Scott R Kelley1, Robert A Vierkant2, Jennifer M Russell3

  • 1Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota.

Diseases of the Colon and Rectum
|September 6, 2024
PubMed
Summary

Diode laser closure for transsphincteric fistula-in-ano offers a continence-preserving treatment option. While initial success rates were 43%, failed cases could undergo delayed fistulotomy, with no new incontinence reported.

Keywords:
CryptoglandularFistula-in-anoLaserRadially emitting diode

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Area of Science:

  • Colorectal Surgery
  • Minimally Invasive Procedures
  • Laser Therapy

Background:

  • Shift in fistula-in-ano treatment towards preserving continence.
  • Radially emitting diode laser catheters used for fistula track ablation since 2011.
  • Previous studies report variable success rates (20%-89%).

Purpose of the Study:

  • To present the authors' experience with managing solitary transsphincteric fistulas.
  • Focus on cryptoglandular origin fistulas treated with a radially emitting diode laser.

Main Methods:

  • Prospective, nonrandomized, single-center trial with 12-month follow-up.
  • Forty-six adult patients with transsphincteric fistula-in-ano underwent diode laser closure.
  • Primary outcome measures: clinical healing and fistula recurrence.

Main Results:

  • Successful closure after one laser treatment in 43% of patients.
  • 50% of failures allowed for delayed fistulotomy due to fistula migration.
  • No new or worsened fecal incontinence; complications included abscesses and fistula migration.

Conclusions:

  • Radially emitting diode laser closure is a viable, continence-preserving option for transsphincteric fistula-in-ano.
  • Procedure failures do not preclude subsequent treatments and may facilitate delayed fistulotomy.
  • Potential complications include abscess formation and fistula migration.