Complete genome sequence of a Histophilus somni strain 91 isolated from a beef calf with pneumonia

Area of Science:

• Veterinary Microbiology
• Genomics
• Bovine Infectious Diseases

Background:

• Histophilus somni is a key pathogen in the bovine respiratory disease complex.
• Bovine respiratory disease causes significant economic losses in the cattle industry.
• Understanding H. somni's genetic makeup is crucial for developing effective control strategies.

Purpose of the Study:

• To sequence and analyze the complete genome of Histophilus somni strain 91.
• To provide a genomic resource for further investigation into H. somni virulence factors and host-pathogen interactions.
• To contribute to the understanding of the genetic basis of bovine respiratory disease.

Main Methods:

• Whole-genome sequencing of Histophilus somni strain 91.
• Bioinformatic analysis of the obtained genome sequence.
• Isolation of the strain from pneumonic lung tissue of a beef calf.

Main Results:

• The complete genome sequence of Histophilus somni strain 91 was successfully obtained.
• The genome provides insights into the genetic repertoire of this important bovine pathogen.
• This genomic data serves as a foundation for comparative genomics and functional studies.

Conclusions:

• The availability of the complete genome sequence of H. somni strain 91 is a valuable resource.
• This resource will facilitate research into the pathogenesis of bovine respiratory disease.
• Further studies utilizing this genome sequence are expected to enhance disease prevention and treatment.