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Updated: Jun 14, 2025
Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies
Published on: December 1, 2023
Prevalence of Tick Infection with Bartonella in China: A Review and Meta-analysis
Yuhua Wang1, Ruishan Li1, Ting Yin1
1Department of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, Xi'an, Shaanxi, China.
Objective:
Bartonellosis is a global vector-borne zoonosis caused by Bartonella, a genus of intracellular Gram-negative bacteria. It is one of 14 emerging infectious diseases that have recently been identified in China, and the prevalence varies by region. A more in-depth understanding is needed regarding the role and influencing factors of ticks in the transmission of Bartonella, including the infection rate of ticks with Bartonella in different regions. This study explored the prevalence of Bartonella in ticks and the factors that influence it.
Methods:
Databases (PubMed, Embase, Elsevier ScienceDirect, Cochrane Library, Web of Science, CNKI, VIP, CBM, and WanFang) were searched to review the preliminary research on Bartonella-carrying ticks in China.
Results:
We identified and included 22 articles. Bartonella infection rates in ticks varied from 0 to 22.79% examined by the included studies. Our meta-analysis revealed that the prevalence of Bartonella in ticks was 3.15% (95% CI: 1.22 - 5.82%); the prevalence was higher in parasitic ticks (4.90%; 95% CI: 1.39 -10.14%) than ticks seeking hosts (1.42%; 95% CI: 0.62 - 2.50%) (P = 0.047).
Conclusion:
The prevalence of Bartonella in the southern region of China (6.45%) was higher than that in the northern region (1.28%) (P = 0.030). Knowledge of ticks' vectors and reservoir competence is crucial to reduce the disease burden.
