Related Experiment Video
Updated: Jun 14, 2025

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Virtual Collaborative Care Versus Specialty Psychiatry Treatment for Depression or Anxiety
Kathryn K Ridout1,2,3, Mubarika Alavi2, Catherine Lee2
1The Permanente Medical Group, Kaiser Permanente Northern California, Oakland, California.
Virtual collaborative care demonstrated equal or greater effectiveness than specialty psychiatry for treating depression and anxiety symptoms. This approach supports national guidelines for mental health screening and treatment.
Area of Science:
- Mental Health
- Psychiatry
- Health Services Research
Background:
- Collaborative care models are recognized for improving depression and anxiety in primary care settings.
- Comparative effectiveness studies of virtual collaborative care versus virtual specialty psychiatry are limited in real-world settings.
- This study addresses the gap by comparing virtual collaborative care and specialty psychiatry for mental health treatment.
Purpose of the Study:
- To compare the effectiveness of virtual collaborative care versus virtual specialty psychiatry in managing depressive and anxiety symptoms over six months.
- To examine patient outcomes in real-world integrated healthcare systems.
Main Methods:
- An observational study using target trial emulation within a large integrated healthcare system.
- Inclusion criteria: adults (≥18 years) with mild-moderate depression or anxiety (PHQ-9/GAD-7 scores). Exclusion criteria: acute suicide risk.
- Statistical analysis involved linear mixed-effects regression with inverse probability of treatment weighting to compare outcomes at 6 months.
Main Results:
- 10,380 patients with depression and 2,935 with anxiety were analyzed.
- Both collaborative care and specialty psychiatry groups showed significant symptom improvement.
- Collaborative care yielded significantly greater symptom reduction for both depression (AMD = -4.0) and anxiety (AMD = -2.6) compared to specialty psychiatry (P < .0001 for both).
Conclusions:
- Virtual collaborative care is as effective as, and potentially more effective than, specialty psychiatry for depression and anxiety.
- Implementation of collaborative care aligns with and supports national guidelines for mental health screening and treatment.
- Virtual collaborative care offers a viable and effective alternative for managing common mental health conditions in integrated care settings.
Related Concept Videos
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Specialized Care Centers and Settings-I
Daycare centers
They provide several functions. Some facilities care for healthy newborns and children whose parents work, while others are medically focused and care for...
Depression: Overview
Drug Therapy
Antianxiety Medications
Group Therapy
Depressive Disorders: MDD and Dysthymia

