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Updated: Jun 14, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Relationship between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn
Jamie L Archambault1, Teri L Hernandez2, Eva S Nozik3
1Section of Neonatology, Department of Pediatrics, University of Colorado, Aurora, CO.
Abstract:
Urine serotonin (5-HT)/creatinine was lower at day of life 3 in newborns with pulmonary hypertension compared with controls, while the percent change in the 5-HT metabolite, 5-hydroxyindoleacetic acid (5-HIAA)/creatinine increased. We speculate that the changes in 5-HT and 5-HIAA reflect enhanced pulmonary 5-HT uptake and/or metabolism.
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