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Updated: Jun 14, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
Published on: April 29, 2010
The replication crisis has led to positive structural, procedural, and community changes
Max Korbmacher1,2,3, Flavio Azevedo4,5, Charlotte R Pennington6
1Department of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway.
Abstract:
The emergence of large-scale replication projects yielding successful rates substantially lower than expected caused the behavioural, cognitive, and social sciences to experience a so-called 'replication crisis'. In this Perspective, we reframe this 'crisis' through the lens of a credibility revolution, focusing on positive structural, procedural and community-driven changes. Second, we outline a path to expand ongoing advances and improvements. The credibility revolution has been an impetus to several substantive changes which will have a positive, long-term impact on our research environment.
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