Hantavirus: Preliminary assessment of lateral flow immune assay prototypes to detect IgM and IgG antibodies
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Published on: February 4, 2012
João Pedro Tôrres Guimarães1, Matheus Bernardes Torres Fogaça1, Rodrigo Scaliante Moura2
1Institute of Tropical Pathology and Public Health /Universidade Federal de Goiás, Goiânia, GO, Brazil.
Three lateral flow immunoassay prototypes developed to detect IgM, IgG and IgM/IgG antibodies against Hantavirus were evaluated. A total of 163 samples were tested: 10 from Hantavirus patients, 103 from related diseases, and 50 from healthy controls. The prototypes exhibited 100 % sensitivity, 97.5 % to 99.3 % specificity, indicating promising improved diagnosis.
Three lateral flow immunoassay prototypes developed to detect IgM, IgG and IgM/IgG antibodies against Hantavirus were evaluated. A total of 163 samples were tested: 10 from Hantavirus patients, 103 from related diseases, and 50 from healthy controls. The prototypes exhibited 100 % sensitivity, 97.5 % to 99.3 % specificity, indicating promising improved diagnosis.
