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Fabrication and Characterization of Thickness Mode Piezoelectric Devices for Atomization and Acoustofluidics

Fabrication and Characterization of Thickness Mode Piezoelectric Devices for Atomization and Acoustofluidics

Published on: August 5, 2020

Fast acoustic droplet ejection based on annular array transducer.

Youta Huang¹, Yang Zhang², Weichang Wu³

¹Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 508055 China; The Key Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, Shenzhen 518055, China; National-Reginoal Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory of Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China; Shenzhen Key Laboratory of Ultrasound Imaging and Therapy, Shenzhen 518055, China.

|September 7, 2024

Summary

This summary is machine-generated.

A novel annular array transducer enhances acoustic droplet ejection (ADE) by enabling dynamic focusing, improving liquid transfer efficiency. This advancement accelerates high-throughput applications in synthetic biology and drug discovery.

Keywords:

Acoustic droplet ejection Annular array transducer Fast liquid transfer

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Area of Science:

Biomedical Engineering
Acoustic Technology

Background:

Acoustic droplet ejection (ADE) is a preferred liquid transfer method for its accuracy and reduced waste.
Current ADE systems use single-element transducers requiring mechanical adjustment, limiting efficiency.
Ultrasound transducers are key for focused beam generation in ADE.

Purpose of the Study:

To develop a high-frequency annular array transducer for ADE.
To enable rapid, dynamic axial focusing without mechanical movement.
To enhance liquid transfer efficiency and speed in ADE systems.

Main Methods:

Design and implementation of a 10 MHz, 5-element annular array transducer.
Testing dynamic axial focusing capabilities.
Evaluating droplet ejection accuracy and stability at various focal lengths.

Main Results:

The annular array transducer demonstrated good dynamic axial focusing ability.
Accurate and stable nanoliter droplet ejection was achieved between 26-32 mm focal lengths.
The new transducer design accelerates liquid transfer compared to traditional methods.

Conclusions:

Annular array transducers offer significant advancements for ADE systems.
This technology improves precision and throughput for critical liquid transfer applications.
The developed transducer is promising for synthetic biology, genotyping, and drug discovery.